ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Comprised of all of ASN's focus areas, the ASN Alliance for Kidney Health allows the society to continue its growth and work towards the goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 22: Issue 4 (Feb 2024): Pregnancy and Kidney Disease is now available online.
RE: lupus management 1 hour ago
Dr. Kim. You may want to access and read the following paper as it has some relevance to your patient. I would recommend that you measure anti-Smit...
View Discussion
RE: lupus management 2 hours ago
Dr. Kim. Interesting question. I don't think that anyone has a good answer. Personally, I think it is combination of auto-antibodies and Complement...
View Discussion
RE: lupus management 3 hours ago
Personally I would not treat a DS DNA by itself. What were the serologies (C3 C4 DS DNA) when the patient was first diagnosed with Class III on ...
View Discussion
RE: lupus management 7 hours ago
thank you for comments. watchful observation is what I am doing,, though I often find clean urinalysis betrays me. Assuming no clinical change ...
View Discussion
RE: lupus management 7 hours ago
thank you for comments. watchful observation is what I am doing,, though I often find clean urinalysis betrays me. Assuming no clinical change ...
View Discussion
RE: lupus management 7 hours ago
thank you for comments. watchful observation is what I am doing,, though I often find clean urinalysis betrays me. Assuming no clinical change ...
View Discussion
RE: lupus management 8 hours ago
With urine normal, I want more (something in the urine, or much worse serology) before I increase treatment assuming she is taking her MMF 3 grams ...
View Discussion
RE: Measuring individual kidney creatinine clearance 8 hours ago
left kidney urine volume 1,100 ml creatinine total, urine 92 mg/g Cr Cl 8 And Right kidney urine volume 2900 ml creatinine total, uri...
View Discussion
RE: Measuring individual kidney creatinine clearance 8 hours ago
57 year-old bedridden with quadriplegia with SPC unclear if intermittent clamped drainage or continuous drainage into the bag done He has several ...
View Discussion
RE: lupus management 10 hours ago
I agree with Dr. Balan's recommendations. In addition, please increase frequency of monitoring of BP, SCr, urinalysis/sediment and UPr/Cr or UAlb/C...
View Discussion
RE: lupus management 10 hours ago
I am not really convinced that serological markers should be treated. Clinically this patient is in remission. I believe you continue the same mana...
View Discussion
LAST CALL: Volunteer by TODAY May 8 to serve as a case report reviewer for Kidney Week 2024! 10 hours ago
ASN invites ASN Fellows-in-Training members to serve as reviewers for case reports submitted by trainees for Kidney Week 2024. The reviewing/gradin...
View Discussion
RE: lupus management 13 hours ago
I assume that the eGFR is normal as well. So the patient is in a complete clinical remission of her kidney disease, but remains serologically activ...
View Discussion
RE: IgA Nephritis and pneumonia, underlying CKD with co morbidities 13 hours ago
IgA vasculitis..hold mmf taper steroid ..after resolution of infection ..consider Rituximab --------------------------------- Alaa Nabih Abdalla ...
View Discussion
RE: lupus management 15 hours ago
Urine is completely bland and normal --------------------------------- Youngho Kim MD Pacific Nephrology Associates Tacoma WA -------------------...
View Discussion
RE: lupus management 15 hours ago
Please give current UPCR or 24 hour proteinuria and eGFR. I assume that the urine sediment is normal. If she is in a complete clinical remission, a...
View Discussion
RE: Membranous nephropathy 18 hours ago
We can help to get that information. Drop me a line. ------------------------------ Quansheng Zhu MD, PhD ImmunoWork Monrovia CA (310) 279-2584 -...
View Discussion
lupus management 19 hours ago
Welcome any comments. Thank you in advance 29 y/o female with lupus, Class III on biopsy in 6/2022. normal Creatinine, mild hematuria resolved ...
View Discussion
RE: IgA Nephritis and pneumonia, underlying CKD with co morbidities 20 hours ago
This is IgA V not Pimary. IgA N. The evidence for efficacy of MMF + Steroids in IgAV is extreme,y weak. I would stop the MMF, , taper steroids and ...
View Discussion
IgA Nephritis and pneumonia, underlying CKD with co morbidities 21 hours ago
Hello, I have 71 year old cKD stage 3/4 baseline cr 2.0 significant co morbidities DM2 A1c ranging 8-9 , systolic CHF EF 33 % , significant...
View Discussion
RE: Progressive renal failure with High ANA, low Complement (C4) and positive cryoglobulins 21 hours ago
My impression is RF positive in both type II and III cyyoglobulinemia Also no vasultic rash which develops almost in every pt with MCS ---------...
View Discussion
RE: Measuring individual kidney creatinine clearance 21 hours ago
Thanks for the data. Tc99-MAG3 is excreted by by both GFR and tubular mechanisms. It is not a true marker of GFR. Tc99 DTPA is exclusively handled ...
View Discussion
RE: Measuring individual kidney creatinine clearance 22 hours ago
left kidney urine volume 1,100 ml creatinine total, urine 92 mg/g Cr Cl 8 And Right kidney urine volume 2900 ml creatinine total, uri...
View Discussion
DUE MAY 8TH: Opportunity for Fellows. Encourage fellows to volunteer as case report reviewers for Kidney Week 2024! 1 day ago
ASN invites ASN Fellows-in-Training members to serve as reviewers for case reports submitted by trainees for Kidney Week 2024. The reviewing/gradin...
View Discussion
RE: Progressive renal failure with High ANA, low Complement (C4) and positive cryoglobulins 1 day ago
Type II or Type III? Type II is "mixed" IgG/IgM CryoIg .Thanks. Let us know the EM findings when available. ------------------------------ Richar...
View Discussion
RE: Progressive renal failure with High ANA, low Complement (C4) and positive cryoglobulins 1 day ago
further discussion today with Immunologist, confirming type III mixed cryoglobulinemia (trace amount). planning to start her on Rituximab soon ...
View Discussion
RE: Young patient with Lupus-like pattern on IF in kidney biopsy 1 day ago
I agree that infection (including Bartonella, Borellua , Q fever, leptospirosis, etc needs to be excluded by appropriate culture and serology. Do y...
View Discussion
RE: Young patient with Lupus-like pattern on IF in kidney biopsy 1 day ago
Kidney and liver are injured . With splenomegaly .Infection should be excluded ..bartonella can cause this full house pattern Leptospirosis can ca...
View Discussion
RE: Progressive renal failure with High ANA, low Complement (C4) and positive cryoglobulins 1 day ago
If this is a "polyclonal " CryoIg why is the RF elevated. Thus suggests a mixed IgG=IgM Type II CryoIg. Could this be old burnt out HCV and a late ...
View Discussion
RE: Progressive renal failure with High ANA, low Complement (C4) and positive cryoglobulins 2 days ago
quantitative cryoglobulin report not available. surprisingly, patient has no features of any vasculitis, neuropathy or arthropathy. she was even ...
View Discussion
RE: Progressive renal failure with High ANA, low Complement (C4) and positive cryoglobulins 2 days ago
Thanks for your response Rheumatoid factor (RF) Latex 48 IU/ml ( normal range < 30) Cyclic citrullinated peptide (CCP) antibodies <1 no prev...
View Discussion
RE: Progressive renal failure with High ANA, low Complement (C4) and positive cryoglobulins 2 days ago
that is a VERy low C4 and this has been described in cryoglobulinemia. Do you have a quantitative amount of the cryoglobulin? ----------...
View Discussion
RE: Progressive renal failure with High ANA, low Complement (C4) and positive cryoglobulins 2 days ago
Thanks for your response Albumin Creatinine ratio is in mg/mmol normal range (0.0 -3.6) Complement C4 level 0.072 (range 0.150 - 0.450 g/L) N...
View Discussion
RE: Nephrotic syndrome treatment 2 days ago
Equivocal staining for IgG and IgM. Nothing remarkable ------------------------------ M Kaisar Nephrologist Brisbane ---------------------------...
View Discussion
RE: Appears to be posting issues here 2 days ago
Seems to be fixed. ------------------------------ Roger Rodby MD, FASN Professor of Medicine Rush University Medical Center Chicago IL (773) 505...
View Discussion
RE: Young patient with Lupus-like pattern on IF in kidney biopsy 2 days ago
seems to be working again ------------------------------ Roger Rodby MD, FASN Professor of Medicine Rush University Medical Center Chicago IL ...
View Discussion
RE: Nephrotic syndrome treatment 2 days ago
HelloWe don't have EM yet. There is a a long delay in getting EM at the moment due to technician issues as all done in a single centre. Sent from ...
View Discussion
RE: Progressive renal failure with High ANA, low Complement (C4) and positive cryoglobulins 2 days ago
What is the Rheumatoid Factor level? How sure are you that the Cryo is polyclonal? Have you tested for HCV viral RNA.? --------------------------...
View Discussion
RE: Nephrotic syndrome treatment 2 days ago
He might be a candidate for RTX. Any "dusting " of IgG in the glomeruli by frozen IF? ------------------------------ Richard Glassock MD, FASN La...
View Discussion
RE: Young patient with Lupus-like pattern on IF in kidney biopsy 2 days ago
this is a test of the software, there have been problems posting. ignore ------------------------------ Roger Rodby MD, FASN Professor of Medici...
View Discussion
Appears to be posting issues here 2 days ago
I think there is a glitch in the software, and posts are not posting. I doubt it is just me, you can try to respond to this But i have been ge...
View Discussion
RE: Nephrotic syndrome treatment 2 days ago
how effaced were the foot processes on EM? ------------------------------ Roger Rodby MD, FASN Professor of Medicine Rush University Medical Cent...
View Discussion
RE: Progressive renal failure with High ANA, low Complement (C4) and positive cryoglobulins 2 days ago
I do not see an explanation for the eGFR of 12, except the ATN. what are the units of albumin creatinine ratio and what are normals for those un...
View Discussion
RE: SGLT2i And eGFR Reduction 2 days ago
GREAT ------------------------------ George Bakris MD, MA, FASN Professor of Medicine, Director, Am.Heart Assoc. Comprehensive Hypertension Cente...
View Discussion
Progressive renal failure with High ANA, low Complement (C4) and positive cryoglobulins 2 days ago
Dear Esteemed members, I would like to discuss an interesting case and would appreciate your thoughts :) A 72 year old Caucasian female (weighs...
View Discussion
Nephrotic syndrome treatment 2 days ago
Good evening I would be grateful for feedback and advise in regards to a 40 year old male with nephrotic syndrome. Presented acutely nephrotic...
View Discussion
RE: Young patient with Lupus-like pattern on IF in kidney biopsy 2 days ago
If a. Infectious cause is excluded , I would give MMF+ low dose steroids. Have you considered C1q nephropathy? Could you post the results of a peri...
View Discussion
RE: Young patient with Lupus-like pattern on IF in kidney biopsy 2 days ago
Antiphosphlipid antibodies were negative. No history of recurrent UTI. ID is involved and suggests to screen for strongyloides, but I will definite...
View Discussion
RE: SGLT2i And eGFR Reduction 2 days ago
In our group we have more stringent HbA1c before we start SGLT2i because we have seen AKID in patient with uncontrolled DM. ---------------------...
View Discussion
RE: SGLT2i And eGFR Reduction 2 days ago
Sheldon thanks for this and as you saw I responded and quoted and updated review in AJN 2022-but agree with what you said obviously in people with ...
View Discussion