ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Comprised of all of ASN's focus areas, the ASN Alliance for Kidney Health allows the society to continue its growth and work towards the goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 22: Issue 4 (Feb 2024): Pregnancy and Kidney Disease is now available online.
RE: Measuring individual kidney creatinine clearance 2 hours ago
Since CT in 12/2022 showed severe left hydronephrosis with cortical atrophy, severe left sided obstruction has been present for at least 16 months....
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ANCA vasculitits 3 hours ago
79 y.o.female with type 2 diabetes, hypertension, and CKD. She presented to me with Creatinine 3.40 mg/dl eGFR 13 ml/min . her only symptom is fati...
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Measuring individual kidney creatinine clearance 4 hours ago
57 y.o. male with PMHx of C7 injury/TB w/ quadriplegia and chronic suprapubic catheter, chronic L severe hydronephrosis, schizophrenia, HTN, DM Typ...
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RE: safety of Immunosuppression start for possibly GPA with history if bacteremia still in utine culture 4 hours ago
Pasting, the latest ANCA profile below that can be compared with the previous Pre treatment in this stem of the question. CRP is better than what i...
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RE: RAI in ESRD-HD 5 hours ago
Thank you so much.Very helpful! ------------------------------ Nazia Junejo MD Las Vegas NV (801) 542-7115 ------------------------------
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RE: RAI in ESRD-HD 5 hours ago
Thank you ------------------------------ Nazia Junejo MD Las Vegas NV (801) 542-7115 ------------------------------
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RE: SGLT2i And eGFR Reduction 6 hours ago
I would stop it, and if creatinine improves restart it at a lower dose. ------------------------------ Roger Rodby MD, FASN Professor of Medicin...
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RE: Sterile Pyuria in a patient with Sjogren's disease 6 hours ago
I have to say this is a tough one, and I suspect there is interstitial nephritis, but is it enough to treat? What if you did a biopsy and found it,...
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RE: RAI in ESRD-HD 6 hours ago
We have done this a couple times, we got complete help from the nuclear medicine department as they deal with the hospital's radioactive materials ...
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RE: RAI in ESRD-HD 7 hours ago
See Holst J et al Thyroid 2005; 15; 1321- 1331. For suggestions on dosage and precautions. ------------------------------ Richard Glassock MD, FA...
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Reminder: Volunteer by May 8 to serve as a case report reviewer for Kidney Week 2024! 7 hours ago
ASN invites ASN Fellows-in-Training members to serve as reviewers for case reports submitted by trainees for Kidney Week 2024. The reviewing/gradin...
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RAI in ESRD-HD 7 hours ago
A HD patient just diagnosed with thyroid ca and is recommended to have RAI.I am not quite sure how to safeguard dialysis staff /equipment . Looks...
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RE: Re: pharmacogenomic studies in resistant HTN 10 hours ago
Thank you Dr Bakris Are there any labs for sending these studies in selected patients ? ------------------------------ [Sriram] [Sriperumbudu...
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RE: SGLT2i And eGFR Reduction 10 hours ago
So does SGLt2i have to be stopped if eGFR falls >30% persistently? --------------------------------- Eho Georges Chicago ------------------------...
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RE: Sterile Pyuria in a patient with Sjogren's disease 10 hours ago
Thank you for replying WBC count varies between 50 - 100 cells per HPF. No other cells. No proteinuria. Urine protein/creatinine ratio = 0.1...
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RE: Sterile Pyuria in a patient with Sjogren's disease 10 hours ago
Thank you for replying. That was my question. should I wait to see evidence of worsening kidney function of a blood test [by that time, she may ...
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RE: SGLT2i And eGFR Reduction 11 hours ago
All drugs that provide renoprotection reduce GFR between 10-30% and stablize. I have listed an editorial review on the topic. ( Bakris GL, Weir MR....
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RE: Re: pharmacogenomic studies in resistant HTN 12 hours ago
Pharmacogenomics focuses on the identification of genetic factors responsible for inter-individual variability in drug response. While there are st...
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RE: Sterile Pyuria in a patient with Sjogren's disease 12 hours ago
Sterile pyuria still could be part of interstitial nephritis and the question here if this patient have normal GFR and no proteinuria what's th...
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RE: Re: pharmacogenomic studies in resistant HTN 12 hours ago
@George Bakris ------------------------------ Roger Rodby MD, FASN Professor of Medicine Rush University Medical Center Chicago IL (773) 505-319...
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Re: pharmacogenomic studies in resistant HTN 12 hours ago
Hello, Is there any data looking at the role of pharmacogenomic studies to understand the kinetics of anti hypertensive drugs among patients with...
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ASN Kidney News Editorial Fellowship 13 hours ago
ASN Kidney News is seeking talented early career nephrologists and scientists with strong review and editing skills for a two-year editorial fellow...
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RE: Metformin toxicity 13 hours ago
Very tricky. If CRRT is available then start of course. If not and the hemodynamics begin to stabilize and lactate is falling then OK to observe. ...
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RE: SGLT2i And eGFR Reduction 19 hours ago
This is a common phenomenon among patients with T2DM treated with SGLT2i (typically added to RASi). It is mostly explained by the action of SGLT2i ...
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SGLT2i And eGFR Reduction 21 hours ago
I have been noticing that at least 20-30% of my patients are losing more than 20 points of eGFR after starting SGLT2i without returning back to bas...
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RE: Sterile Pyuria in a patient with Sjogren's disease 1 day ago
How many WBCs? PCr ratio and AlbCr ratio? serum bicarb and urine pH? normal creatinine can be very deceiving and does not r/o CIN. ---...
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RE: Sterile Pyuria in a patient with Sjogren's disease 1 day ago
Any white cell casts? What about proteinuria and albuminuria? What does the abdominal ultrasound show. ? Any hypercalcemia or hypercalciuria.. A ki...
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Sterile Pyuria in a patient with Sjogren's disease 1 day ago
Hello everyone, what do you think about a patient with a history of Sjogren's syndrome with persistent sterile pyuria and normal kidney function...
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RE: Metformin toxicity 1 day ago
The @ serves as the ------------------------------ Roger Rodby MD, FASN Professor of Medicine Rush University Medical Center Chicago IL (773) ...
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RE: Metformin toxicity 1 day ago
It's like the bat-signal - someone said "toxicity" or "poisoning," and, regardless of the excellent advice already offered by Dr. Rodby, the siren ...
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RE: Metformin toxicity 1 day ago
absolutely, and the ability to "tag" (@) someone you think may be an authority on the subject and get their response is such a plus. In this case...
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RE: Metformin toxicity 1 day ago
This kind of dialogue is what makes the Open Forum so great. It is like witnessing a bedside consultation involving world renowned experts. More th...
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RE: Metformin toxicity 1 day ago
Are you willing to be wrong, bc it will be too late once you figure that out. And even if the patient is unstable BP, the improvement in Acid bas...
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RE: Metformin toxicity 1 day ago
Personally I don't, but it is case to case management there. I don't think you'll ever find good guidance. If the lactate is disproportionately e...
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RE: Metformin toxicity 1 day ago
Thanks . What if the patient is clearly septic? Do you initiate dialysis right away on the basis (ie no other indication) that the patient had...
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RE: Metformin toxicity 1 day ago
If you think there's a more likely than not chance it's metformin (no fever, no clear source of sepsis, hypothermia), personally I'd recommend HD. ...
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RE: Metformin toxicity 1 day ago
opinion Metformin induced lactic acidosis has a high mortality Dialysis removes the Metformin and improves the acidosis For just about all po...
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Metformin toxicity 1 day ago
Pt with previously normal GFR on Metformin presents with what seems like septic shock and severe lactic acidosis, requiring pressors. For the pur...
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RE: IgG kappa MGRS x3: recrudescence and worse response to cybord- time for rebiopsy? 1 day ago
Here is the bone marrow biopsy report from 2018: Final Diagnosis: Bone marrow core biopsy: - Normocellular marrow with plasma cells compris...
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RE: IgG kappa MGRS x3: recrudescence and worse response to cybord- time for rebiopsy? 2 days ago
Dr. Leung. I will remember this key advice. Do the FiSH results any bearing on CAR-T cell therapy? ------------------------------ Richard Glassoc...
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RE: IgG kappa MGRS x3: recrudescence and worse response to cybord- time for rebiopsy? 2 days ago
Plasma cells with t(11;14) often do not have a very good response to bortezomib. Daratumumab increases the responsiveness, but resistance can be se...
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RE: IgG kappa MGRS x3: recrudescence and worse response to cybord- time for rebiopsy? 2 days ago
Could you explain how the FISH results on a bone narrow biopsy will influence the treatment decisions in this case?. The answer to this question is...
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RE: safety of Immunosuppression start for possibly GPA with history if bacteremia still in utine culture 2 days ago
Here is another often missed association - staph lugdunensis bacteremia and infective endocarditis. It's not your ordinary coagulase-negative staph...
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RE: IgG kappa MGRS x3: recrudescence and worse response to cybord- time for rebiopsy? 2 days ago
The FISH I was asking for is the myeloma FISH from the bone marrow biopsy. ------------------------------ Nelson Leung MD Mayo Clinic Rochester M...
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RE: Membranous nephropathy 2 days ago
Depending on what is happening with Anti-PlA2R antibody levels and (if available) CD19/CD20 B cell counts in peripheral blood, re-dosing with RTX (...
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RE: Membranous nephropathy 2 days ago
The patient received Rituxan x 2 dose with last dose 5 months back. Usually we give Rituxan after 6 months. I guess we can give it sooner at 5 mont...
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RE: safety of Immunosuppression start for possibly GPA with history if bacteremia still in utine culture 3 days ago
Following case report is relevant to the points made by Dr. Rodby regarding Streptococcus fecalis bacteremia and endocarditis complicating colon ca...
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RE: IgG kappa MGRS x3: recrudescence and worse response to cybord- time for rebiopsy? 3 days ago
addendum- FISH us often done on kidney allograft biopsies (to identify viral infection, such as BK virus) and it has been done to identify mutant D...
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RE: IgG kappa MGRS x3: recrudescence and worse response to cybord- time for rebiopsy? 3 days ago
The findings in this case clearly indicate a PGNMID. No need for Pronase digestion and paraffin IF or LD/MS , in my opinion. FISH is only done on b...
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RE: IgG kappa MGRS x3: recrudescence and worse response to cybord- time for rebiopsy? 3 days ago
Is there case for promise digestion in these cases of mgrs? And when to use it? Is fish routinely done on kidney biopsy? Is there any point of us...
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