ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Comprised of all of ASN's focus areas, the ASN Alliance for Kidney Health allows the society to continue its growth and work towards the goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 22: Issue 4 (Feb 2024): Pregnancy and Kidney Disease is now available online.
RE: Dialysis in delayed presentation of EG ingestion 9 minutes ago
We have seen less EG toxicity in dogs, but this is something we've encountered for decades. Dialyzing them shortly after ingestion has favorable ou...
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RE: PSGN in cirrhosis 17 minutes ago
Could low C3 be due to decreased production by the cirrhotic liver rather than consumption? Thanks ------------------------------ Mowaffaq ----...
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RE: PSGN in cirrhosis 2 hours ago
Seems surprising that no C3 deposition was seen on IF. Especially with such strong stain for IGA and IgG ------------------------------ Satish Ba...
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RE: Lupus In pregnancy 2 hours ago
Thanks- with a complete clinical and serological remission and no relapses for 4 years, the risk of a shift to AzA and/or a pregnancy provoking a r...
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RE: Lupus In pregnancy 3 hours ago
No urine analysis negative done on same setting ESR / CRP not elevated c3/c3 never consumed attached her previous biops...
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RE: Lupus In pregnancy 3 hours ago
Thanks- the absence of hydroxychloroquine therapy may increase the risks of a relapse a bit , but I would not increase the steroids until she is pr...
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RE: ASN Kidney News Editorial Fellowship 6 hours ago
hola interesado en la beca soy colombiano ------------------------------ Juan Conde DrMed CLINICA DE LA COSTA BARRANQUILLA 57 3008370746 -------...
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RE: Lupus In pregnancy 10 hours ago
Thanks a lot for this useful discussion Actually she has no relapses for 4 years , I switched to Azathioprine 2mg/kg yesterday she was ...
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RE: IgA Nephritis and pneumonia, underlying CKD with co morbidities 12 hours ago
Thanks All for your feedback so will watch him on supportive care I guess main question he already has several risk factors for his CKD progres...
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RE: PSGN in cirrhosis 17 hours ago
See this 30 year old paper. Nothing new under the sun. Keller CK, et al, Q. JMed 1994; 87: 97-102. The association of PSGN with alcoholic cirrhosis...
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RE: PSGN in cirrhosis 18 hours ago
What about the possibility of PSGN superimposed on a pre-existing hepatic Glomerulopathy ? . Difficult to prove, but entirely reasonable . There ar...
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RE: Dialysis in delayed presentation of EG ingestion 18 hours ago
It would seem that once a calcium oxalate crystal is formed/deposited in the interstitium of the kidney (and other organs ) following a bot of acut...
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PSGN in cirrhosis 19 hours ago
We would be interested in your opinion on this case: A 54-year-old man, recently diagnosed with alcoholic liver cirrhosis, presented with abdomina...
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RE: Dialysis in delayed presentation of EG ingestion 1 day ago
Agree that this is a late presentation since a creatinine of 14 would require days to evolve (assuming normal baseline kidney function) as evidence...
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RE: IgA Nephritis and pneumonia, underlying CKD with co morbidities 1 day ago
Dr. Vogt. Thanks- the Ballardie-Robert's finding of efficacy of CYC -steroids in non-crescentic IgA N (not IgAV) was not confirmed by the STOP-IgAN...
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RE: Lupus In pregnancy 1 day ago
in addition to changing MMF to azathioprine, and bumping up the steroids a bit (maybe total 15-20/d?) and checking for APAbs , I would add aspirin ...
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RE: LAST CALL: Volunteer by TODAY May 8 to serve as a case report reviewer for Kidney Week 2024! 1 day ago
Is it still possible to be a fellow reviewer? Patrick Sent from my iPhone
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RE: Dialysis in delayed presentation of EG ingestion 1 day ago
That is a rough case. The largest cohort of patients with AKI after ethylene glycol poisoning who required dialysis that I am aware of is in an a...
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RE: Lupus In pregnancy 1 day ago
Hi there I would like to talk to you about lupus nephritis.It is very much common in females with 9:1 ratio and is being graded according to Histop...
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RE: IgA Nephritis and pneumonia, underlying CKD with co morbidities 1 day ago
PS: We still give cyclophosphamide in severe cases, most when visceral involvement not studies in the Pillebout et al. publication, see pic attache...
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RE: Lupus In pregnancy 1 day ago
Thanks Dr. Vogt for your comment. I should add that patients with SLE, with or without LN should be tested for anti-phospholipid antibodies as t...
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RE: IgA Nephritis and pneumonia, underlying CKD with co morbidities 1 day ago
Thank you Prof. Glassock. This publicaiton I always have difficulties to find! This and the Ballardie paper are the two main publications on this t...
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RE: IgA Nephritis and pneumonia, underlying CKD with co morbidities 1 day ago
Thanks Dr. Vogt. A single RCT of CYC aded to steroids showed no efficacy imn adults with severe IgAV (see Pillebout, E et al Kidney Int, 2010. ) ...
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RE: lupus management 1 day ago
Thanks for the clarification. Thus , the ability to predict a relapse of LN from serology varies from patient to patient. In some patients the corr...
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RE: lupus management 1 day ago
In this patient I cannot quantify the risk of relapse .. But if a patient relapses after I month or 2 months ( less or more) of serological activit...
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RE: IgA Nephritis and pneumonia, underlying CKD with co morbidities 1 day ago
The rash in legs, with IgA in skin biopsy is Henoch Schönlein purpura. Usually, the skin lesions in adult are not purpura but small necrosis and in...
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RE: lupus management 1 day ago
Thank you for valuable comments! At the time of diagnosis, dsDNA ~300, C3 31 C4 2. Upcr 2.3. I guess she is not there yet at least serologicall...
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RE: Lupus In pregnancy 1 day ago
We do exactly what Prof Glassock proposed, switching from MMF to Azathioprine. Intensification of steroid dosing after conception may be appropriat...
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RE: Lupus In pregnancy 1 day ago
A switch from MMF to Azathioprine in this patient can very likely be achieved without a major risk of relapse - however , such a relapse does have ...
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RE: lupus management 1 day ago
I am not sure I understand what you mean by "trend.". In this patient, the serum anti-deDNA antibody levels are increasing and the Complement level...
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RE: lupus management 1 day ago
Some patients go to clinical relapse after serological activity...others don't If we know the trend of the patient we can choose whom we can optim...
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RE: Lupus In pregnancy 1 day ago
Urine analysis no Active sediments antiphospholipid AB pending CRP / ESR not elevated c3/ c4 not consumed ( done last month) anti ds DNA ...
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RE: Lupus In pregnancy 1 day ago
What does the urine sediment show ? What is the serology-C3/ C4, anti-dsDNA, anti-Smith antibody?, ------------------------------ Richard Glassoc...
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Lupus In pregnancy 1 day ago
35 years old female patient known SLE and lupus nephritis class III/IV ( renal biopsy on 2019) history of thyroid cancer with total thyroidectom...
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RE: Dialysis in delayed presentation of EG ingestion 1 day ago
A week out and still oliguric not a good prognosis but Im not ready to give up Still, see attached "Patient 1 was started on continuous veno...
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RE: Dialysis in delayed presentation of EG ingestion 1 day ago
With diffuse calcium oxalate deposition in the kidney and oliguric AKI, the expectation for a full recovery of kidney function is very low, and the...
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RE: Dialysis in delayed presentation of EG ingestion 1 day ago
Thank you Dr Rodby. Yes, she continues to be oliguric. ------------------------------ Naveen Trehan MD Arkansas Renal Group Hot Springs AR (31...
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RE: lupus management 2 days ago
Thanks Dr. Hirsch and Dr. Balan for your erudite and well-reasoned arguments for a conservative, watch and wait strategy for this patient with LN i...
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RE: Dialysis in delayed presentation of EG ingestion 2 days ago
when EG is delayed you will see exactly that, EG level gone and now presently only with the AKII, and there is no reason to dialyze for EG, but as ...
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RE: lupus management 2 days ago
"The serological findings are viewed as largely irrelevant to clinical treatment decisions." I can only speak anecdotally on this but I find tha...
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RE: lupus management 2 days ago
While I do not believe that this patient requires an increase in immunosuppression, I do not negate the value of serology. I don't perform serology...
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RE: lupus management 2 days ago
I have followed the "majority" in basing decisions on clinical signs. Therefore, I don't order serology. However, it's somewhat of a non-issue sinc...
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Dialysis in delayed presentation of EG ingestion 2 days ago
Hello, I wanted to get some information on indications of dialysis in delayed presentation of EG toxicity. Have a 24 yr old young caucasian wh...
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RE: lupus management 2 days ago
The Majority view (so far) is that this patient does not need any change in therapy so long as complete clinical remission is obtained and persists...
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RE: lupus management 2 days ago
Thanks Dr. Rodby for your worthy contribution to this debate. I full understand your reluctance to add any medication when the patient is doing so ...
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RE: lupus management 2 days ago
I have no issue with adding belimumab , but I dont know if it had been shown to be of value as a maintenance agent for lupus nephritis. The only do...
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RE: lupus management 2 days ago
Dr. Kim. You may want to access and read the following paper as it has some relevance to your patient. I would recommend that you measure anti-Smit...
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RE: lupus management 2 days ago
Dr. Kim. Interesting question. I don't think that anyone has a good answer. Personally, I think it is combination of auto-antibodies and Complement...
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RE: lupus management 2 days ago
Personally I would not treat a DS DNA by itself. What were the serologies (C3 C4 DS DNA) when the patient was first diagnosed with Class III on ...
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RE: lupus management 2 days ago
thank you for comments. watchful observation is what I am doing,, though I often find clean urinalysis betrays me. Assuming no clinical change ...
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